Models, code, and papers for "Daniel King":

ScispaCy: Fast and Robust Models for Biomedical Natural Language Processing

Feb 21, 2019
Mark Neumann, Daniel King, Iz Beltagy, Waleed Ammar

Despite recent advances in natural language processing, many statistical models for processing text perform extremely poorly under domain shift. Processing biomedical and clinical text is a critically important application area of natural language processing, for which there are few robust, practical, publicly available models. This paper describes scispaCy, a new tool for practical biomedical/scientific text processing, which heavily leverages the spaCy library. We detail the performance of two packages of models released in scispaCy and demonstrate their robustness on several tasks and datasets. Models and code are available at

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Pretrained Language Models for Sequential Sentence Classification

Sep 22, 2019
Arman Cohan, Iz Beltagy, Daniel King, Bhavana Dalvi, Daniel S. Weld

As a step toward better document-level understanding, we explore classification of a sequence of sentences into their corresponding categories, a task that requires understanding sentences in context of the document. Recent successful models for this task have used hierarchical models to contextualize sentence representations, and Conditional Random Fields (CRFs) to incorporate dependencies between subsequent labels. In this work, we show that pretrained language models, BERT (Devlin et al., 2018) in particular, can be used for this task to capture contextual dependencies without the need for hierarchical encoding nor a CRF. Specifically, we construct a joint sentence representation that allows BERT Transformer layers to directly utilize contextual information from all words in all sentences. Our approach achieves state-of-the-art results on four datasets, including a new dataset of structured scientific abstracts.

* EMNLP 2019 

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Strong Baselines for Complex Word Identification across Multiple Languages

Apr 11, 2019
Pierre Finnimore, Elisabeth Fritzsch, Daniel King, Alison Sneyd, Aneeq Ur Rehman, Fernando Alva-Manchego, Andreas Vlachos

Complex Word Identification (CWI) is the task of identifying which words or phrases in a sentence are difficult to understand by a target audience. The latest CWI Shared Task released data for two settings: monolingual (i.e. train and test in the same language) and cross-lingual (i.e. test in a language not seen during training). The best monolingual models relied on language-dependent features, which do not generalise in the cross-lingual setting, while the best cross-lingual model used neural networks with multi-task learning. In this paper, we present monolingual and cross-lingual CWI models that perform as well as (or better than) most models submitted to the latest CWI Shared Task. We show that carefully selected features and simple learning models can achieve state-of-the-art performance, and result in strong baselines for future development in this area. Finally, we discuss how inconsistencies in the annotation of the data can explain some of the results obtained.

* NAACL 2019 

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Assessing the Impact of Blood Pressure on Cardiac Function Using Interpretable Biomarkers and Variational Autoencoders

Aug 13, 2019
Esther Puyol-Antón, Bram Ruijsink, James R. Clough, Ilkay Oksuz, Daniel Rueckert, Reza Razavi, Andrew P. King

Maintaining good cardiac function for as long as possible is a major concern for healthcare systems worldwide and there is much interest in learning more about the impact of different risk factors on cardiac health. The aim of this study is to analyze the impact of systolic blood pressure (SBP) on cardiac function while preserving the interpretability of the model using known clinical biomarkers in a large cohort of the UK Biobank population. We propose a novel framework that combines deep learning based estimation of interpretable clinical biomarkers from cardiac cine MR data with a variational autoencoder (VAE). The VAE architecture integrates a regression loss in the latent space, which enables the progression of cardiac health with SBP to be learnt. Results on 3,600 subjects from the UK Biobank show that the proposed model allows us to gain important insight into the deterioration of cardiac function with increasing SBP, identify key interpretable factors involved in this process, and lastly exploit the model to understand patterns of positive and adverse adaptation of cardiac function.

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dAUTOMAP: decomposing AUTOMAP to achieve scalability and enhance performance

Sep 25, 2019
Jo Schlemper, Ilkay Oksuz, James R. Clough, Jinming Duan, Andrew P. King, Julia A. Schnabel, Joseph V. Hajnal, Daniel Rueckert

AUTOMAP is a promising generalized reconstruction approach, however, it is not scalable and hence the practicality is limited. We present dAUTOMAP, a novel way for decomposing the domain transformation of AUTOMAP, making the model scale linearly. We show dAUTOMAP outperforms AUTOMAP with significantly fewer parameters.

* Presented at ISMRM 27th Annual Meeting & Exhibition (Abstract #658) 

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Deep Learning using K-space Based Data Augmentation for Automated Cardiac MR Motion Artefact Detection

Aug 31, 2018
Ilkay Oksuz, Bram Ruijsink, Esther Puyol-Anton, Aurelien Bustin, Gastao Cruz, Claudia Prieto, Daniel Rueckert, Julia A. Schnabel, Andrew P. King

Quality assessment of medical images is essential for complete automation of image processing pipelines. For large population studies such as the UK Biobank, artefacts such as those caused by heart motion are problematic and manual identification is tedious and time-consuming. Therefore, there is an urgent need for automatic image quality assessment techniques. In this paper, we propose a method to automatically detect the presence of motion-related artefacts in cardiac magnetic resonance (CMR) images. As this is a highly imbalanced classification problem (due to the high number of good quality images compared to the low number of images with motion artefacts), we propose a novel k-space based training data augmentation approach in order to address this problem. Our method is based on 3D spatio-temporal Convolutional Neural Networks, and is able to detect 2D+time short axis images with motion artefacts in less than 1ms. We test our algorithm on a subset of the UK Biobank dataset consisting of 3465 CMR images and achieve not only high accuracy in detection of motion artefacts, but also high precision and recall. We compare our approach to a range of state-of-the-art quality assessment methods.

* Accepted for MICCAI2018 Conference 

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Detection and Correction of Cardiac MR Motion Artefacts during Reconstruction from K-space

Jun 12, 2019
lkay Oksuz, James Clough, Bram Ruijsink, Esther Puyol-Anton, Aurelien Bustin, Gastao Cruz, Claudia Prieto, Daniel Rueckert, Andrew P. King, Julia A. Schnabel

In fully sampled cardiac MR (CMR) acquisitions, motion can lead to corruption of k-space lines, which can result in artefacts in the reconstructed images. In this paper, we propose a method to automatically detect and correct motion-related artefacts in CMR acquisitions during reconstruction from k-space data. Our correction method is inspired by work on undersampled CMR reconstruction, and uses deep learning to optimize a data-consistency term for under-sampled k-space reconstruction. Our main methodological contribution is the addition of a detection network to classify motion-corrupted k-space lines to convert the problem of artefact correction to a problem of reconstruction using the data consistency term. We train our network to automatically correct for motion-related artefacts using synthetically corrupted cine CMR k-space data as well as uncorrupted CMR images. Using a test set of 50 2D+time cine CMR datasets from the UK Biobank, we achieve good image quality in the presence of synthetic motion artefacts. We quantitatively compare our method with a variety of techniques for recovering good image quality and showcase better performance compared to state of the art denoising techniques with a PSNR of 37.1. Moreover, we show that our method preserves the quality of uncorrupted images and therefore can be also utilized as a general image reconstruction algorithm.

* Accepted to MICCAI 2019. arXiv admin note: text overlap with arXiv:1808.05130 

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Automatic CNN-based detection of cardiac MR motion artefacts using k-space data augmentation and curriculum learning

Oct 29, 2018
lkay Oksuz, Bram Ruijsink, Esther Puyol-Anton, James Clough, Gastao Cruz, Aurelien Bustin, Claudia Prieto, Rene Botnar, Daniel Rueckert, Julia A. Schnabel, Andrew P. King

Good quality of medical images is a prerequisite for the success of subsequent image analysis pipelines. Quality assessment of medical images is therefore an essential activity and for large population studies such as the UK Biobank (UKBB), manual identification of artefacts such as those caused by unanticipated motion is tedious and time-consuming. Therefore, there is an urgent need for automatic image quality assessment techniques. In this paper, we propose a method to automatically detect the presence of motion-related artefacts in cardiac magnetic resonance (CMR) cine images. We compare two deep learning architectures to classify poor quality CMR images: 1) 3D spatio-temporal Convolutional Neural Networks (3D-CNN), 2) Long-term Recurrent Convolutional Network (LRCN). Though in real clinical setup motion artefacts are common, high-quality imaging of UKBB, which comprises cross-sectional population data of volunteers who do not necessarily have health problems creates a highly imbalanced classification problem. Due to the high number of good quality images compared to the relatively low number of images with motion artefacts, we propose a novel data augmentation scheme based on synthetic artefact creation in k-space. We also investigate a learning approach using a predetermined curriculum based on synthetic artefact severity. We evaluate our pipeline on a subset of the UK Biobank data set consisting of 3510 CMR images. The LRCN architecture outperformed the 3D-CNN architecture and was able to detect 2D+time short axis images with motion artefacts in less than 1ms with high recall. We compare our approach to a range of state-of-the-art quality assessment methods. The novel data augmentation and curriculum learning approaches both improved classification performance achieving overall area under the ROC curve of 0.89.

* Submitted to Medical Image Analysis 

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Human-level Performance On Automatic Head Biometrics In Fetal Ultrasound Using Fully Convolutional Neural Networks

Apr 24, 2018
Matthew Sinclair, Christian F. Baumgartner, Jacqueline Matthew, Wenjia Bai, Juan Cerrolaza Martinez, Yuanwei Li, Sandra Smith, Caroline L. Knight, Bernhard Kainz, Jo Hajnal, Andrew P. King, Daniel Rueckert

Measurement of head biometrics from fetal ultrasonography images is of key importance in monitoring the healthy development of fetuses. However, the accurate measurement of relevant anatomical structures is subject to large inter-observer variability in the clinic. To address this issue, an automated method utilizing Fully Convolutional Networks (FCN) is proposed to determine measurements of fetal head circumference (HC) and biparietal diameter (BPD). An FCN was trained on approximately 2000 2D ultrasound images of the head with annotations provided by 45 different sonographers during routine screening examinations to perform semantic segmentation of the head. An ellipse is fitted to the resulting segmentation contours to mimic the annotation typically produced by a sonographer. The model's performance was compared with inter-observer variability, where two experts manually annotated 100 test images. Mean absolute model-expert error was slightly better than inter-observer error for HC (1.99mm vs 2.16mm), and comparable for BPD (0.61mm vs 0.59mm), as well as Dice coefficient (0.980 vs 0.980). Our results demonstrate that the model performs at a level similar to a human expert, and learns to produce accurate predictions from a large dataset annotated by many sonographers. Additionally, measurements are generated in near real-time at 15fps on a GPU, which could speed up clinical workflow for both skilled and trainee sonographers.

* EMBC 2018 

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An Ontology-based Approach to Explaining Artificial Neural Networks

Jun 19, 2019
Roberto Confalonieri, Fermín Moscoso del Prado, Sebastia Agramunt, Daniel Malagarriga, Daniele Faggion, Tillman Weyde, Tarek R. Besold

Explainability in Artificial Intelligence has been revived as a topic of active research by the need of conveying safety and trust to users in the `how' and `why' of automated decision-making. Whilst a plethora of approaches have been developed for post-hoc explainability, only a few focus on how to use domain knowledge, and how this influences the understandability of an explanation from the users' perspective. In this paper we show how ontologies help the understandability of interpretable machine learning models, such as decision trees. In particular, we build on Trepan, an algorithm that explains artificial neural networks by means of decision trees, and we extend it to include ontologies modeling domain knowledge in the process of generating explanations. We present the results of a user study that measures the understandability of decision trees in domains where explanations are critical, namely, in finance and medicine. Our study shows that decision trees taking into account domain knowledge during generation are more understandable than those generated without the use of ontologies.

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Efficient Machine Learning for Large-Scale Urban Land-Use Forecasting in Sub-Saharan Africa

Aug 01, 2019
Daniel Omeiza

Urbanization is a common phenomenon in developing countries and it poses serious challenges when not managed effectively. Lack of proper planning and management may cause the encroachment of urban fabrics into reserved or special regions which in turn can lead to an unsustainable increase in population. Ineffective management and planning generally leads to depreciated standard of living, where physical hazards like traffic accidents and disease vector breeding become prevalent. In order to support urban planners and policy makers in effective planning and accurate decision making, we investigate urban land-use in sub-Saharan Africa. Land-use dynamics serves as a crucial parameter in current strategies and policies for natural resource management and monitoring. Focusing on Nairobi, we use an efficient deep learning approach with patch-based prediction to classify regions based on land-use from 2004 to 2018 on a quarterly basis. We estimate changes in land-use within this period, and using the Autoregressive Integrated Moving Average (ARIMA) model, our results forecast land-use for a given future date. Furthermore, we provide labelled land-use maps which will be helpful to urban planners.

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Worst-Case Regret Bounds for Exploration via Randomized Value Functions

Jun 22, 2019
Daniel Russo

This paper studies a recent proposal to use randomized value functions to drive exploration in reinforcement learning. These randomized value functions are generated by injecting random noise into the training data, making the approach compatible with many popular methods for estimating parameterized value functions. By providing a worst-case regret bound for tabular finite-horizon Markov decision processes, we show that planning with respect to these randomized value functions can induce provably efficient exploration.

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On Learning to Prove

Apr 26, 2019
Daniel Huang

In this paper, we consider the problem of learning a (first-order) theorem prover where we use a representation of beliefs in mathematical claims instead of a proof system to search for proofs. The inspiration for doing so comes from the practices of human mathematicians where a proof system is typically used after the fact to justify a sequence of intuitive steps obtained by "plausible reasoning" rather than to discover them. Towards this end, we introduce a probabilistic representation of beliefs in first-order statements based on first-order distributive normal forms (dnfs) devised by the philosopher Jaakko Hintikka. Notably, the representation supports Bayesian update and does not enforce that logically equivalent statements are assigned the same probability---otherwise, we would end up in a circular situation where we require a prover in order to assign beliefs. We then examine (1) conjecturing as (statistical) model selection and (2) an alternating-turn proving game amenable (in principle) to self-play training to learn a prover that is both complete in the limit and sound provided that players maintain "reasonable" beliefs. Dnfs have super-exponential space requirements so the ideas in this paper should be taken as conducting a thought experiment on "learning to prove". As a step towards making the ideas practical, we will comment on how abstractions can be used to control the space requirements at the cost of completeness.

* Preprint 

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Using Motion and Internal Supervision in Object Recognition

Dec 13, 2018
Daniel Harari

In this thesis we address two related aspects of visual object recognition: the use of motion information, and the use of internal supervision, to help unsupervised learning. These two aspects are inter-related in the current study, since image motion is used for internal supervision, via the detection of spatiotemporal events of active-motion and the use of tracking. Most current work in object recognition deals with static images during both learning and recognition. In contrast, we are interested in a dynamic scene where visual processes, such as detecting motion events and tracking, contribute spatiotemporal information, which is useful for object attention, motion segmentation, 3-D understanding and object interactions. We explore the use of these sources of information in both learning and recognition processes. In the first part of the work, we demonstrate how motion can be used for adaptive detection of object-parts in dynamic environments, while automatically learning new object appearances and poses. In the second and main part of the study we develop methods for using specific types of visual motion to solve two difficult problems in unsupervised visual learning: learning to recognize hands by their appearance and by context, and learning to extract direction of gaze. We use our conclusions in this part to propose a model for several aspects of learning by human infants from their visual environment.

* PhD dissertation, 87 pages, 51 figures, 7 tables 

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Economics of Human-AI Ecosystem: Value Bias and Lost Utility in Multi-Dimensional Gaps

Nov 19, 2018
Daniel Muller

In recent years, artificial intelligence (AI) decision-making and autonomous systems became an integrated part of the economy, industry, and society. The evolving economy of the human-AI ecosystem raising concerns regarding the risks and values inherited in AI systems. This paper investigates the dynamics of creation and exchange of values and points out gaps in perception of cost-value, knowledge, space and time dimensions. It shows aspects of value bias in human perception of achievements and costs that encoded in AI systems. It also proposes rethinking hard goals definitions and cost-optimal problem-solving principles in the lens of effectiveness and efficiency in the development of trusted machines. The paper suggests a value-driven with cost awareness strategy and principles for problem-solving and planning of effective research progress to address real-world problems that involve diverse forms of achievements, investments, and survival scenarios.

* 8 pages, typos corrected, examples added to Table 1 

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Understanding Deep Neural Networks Using Topological Data Analysis

Oct 31, 2018
Daniel Goldfarb

Deep neural networks (DNN) are black box algorithms. They are trained using a gradient descent back propagation technique which trains weights in each layer for the sole goal of minimizing training error. Hence, the resulting weights cannot be directly explained. Using Topological Data Analysis (TDA) we can get an insight on how the neural network is thinking, specifically by analyzing the activation values of validation images as they pass through each layer.

* 13 pages, 14 figures 

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NengoDL: Combining deep learning and neuromorphic modelling methods

May 30, 2018
Daniel Rasmussen

NengoDL is a software framework designed to combine the strengths of neuromorphic modelling and deep learning. NengoDL allows users to construct biologically detailed neural models, intermix those models with deep learning elements (such as convolutional networks), and then efficiently simulate those models in an easy-to-use, unified framework. In addition, NengoDL allows users to apply deep learning training methods to optimize the parameters of biological neural models. In this paper we present basic usage examples, benchmarking, and details on the key implementation elements of NengoDL. More details can be found at .

* 22 pages, 9 figures; v2 fixes a link in the metadata 

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A State Space Approach for Piecewise-Linear Recurrent Neural Networks for Reconstructing Nonlinear Dynamics from Neural Measurements

Dec 23, 2016
Daniel Durstewitz

The computational properties of neural systems are often thought to be implemented in terms of their network dynamics. Hence, recovering the system dynamics from experimentally observed neuronal time series, like multiple single-unit (MSU) recordings or neuroimaging data, is an important step toward understanding its computations. Ideally, one would not only seek a state space representation of the dynamics, but would wish to have access to its governing equations for in-depth analysis. Recurrent neural networks (RNNs) are a computationally powerful and dynamically universal formal framework which has been extensively studied from both the computational and the dynamical systems perspective. Here we develop a semi-analytical maximum-likelihood estimation scheme for piecewise-linear RNNs (PLRNNs) within the statistical framework of state space models, which accounts for noise in both the underlying latent dynamics and the observation process. The Expectation-Maximization algorithm is used to infer the latent state distribution, through a global Laplace approximation, and the PLRNN parameters iteratively. After validating the procedure on toy examples, the approach is applied to MSU recordings from the rodent anterior cingulate cortex obtained during performance of a classical working memory task, delayed alternation. A model with 5 states turned out to be sufficient to capture the essential computational dynamics underlying task performance, including stimulus-selective delay activity. The estimated models were rarely multi-stable, but rather were tuned to exhibit slow dynamics in the vicinity of a bifurcation point. In summary, the present work advances a semi-analytical (thus reasonably fast) maximum-likelihood estimation framework for PLRNNs that may enable to recover the relevant dynamics underlying observed neuronal time series, and directly link them to computational properties.

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