Add to Chrome
Add to Firefox
Add to EdgeHanyu Chen
CT Synthesis with Conditional Diffusion Models for Abdominal Lymph Node Segmentation
Mar 26, 2024
Despite the significant success achieved by deep learning methods in medical image segmentation, researchers still struggle in the computer-aided diagnosis of abdominal lymph nodes due to the complex abdominal environment, small and indistinguishable lesions, and limited annotated data. To address these problems, we present a pipeline that integrates the conditional diffusion model for lymph node generation and the nnU-Net model for lymph node segmentation to improve the segmentation performance of abdominal lymph nodes through synthesizing a diversity of realistic abdominal lymph node data. We propose LN-DDPM, a conditional denoising diffusion probabilistic model (DDPM) for lymph node (LN) generation. LN-DDPM utilizes lymph node masks and anatomical structure masks as model conditions. These conditions work in two conditioning mechanisms: global structure conditioning and local detail conditioning, to distinguish between lymph nodes and their surroundings and better capture lymph node characteristics. The obtained paired abdominal lymph node images and masks are used for the downstream segmentation task. Experimental results on the abdominal lymph node datasets demonstrate that LN-DDPM outperforms other generative methods in the abdominal lymph node image synthesis and better assists the downstream abdominal lymph node segmentation task.
Mitigating Data Consistency Induced Discrepancy in Cascaded Diffusion Models for Sparse-view CT Reconstruction
Mar 14, 2024
Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer from the training-sampling discrepancy, they provide a potential solution to the problem. This study introduces a novel Cascaded Diffusion with Discrepancy Mitigation (CDDM) framework, including the low-quality image generation in latent space and the high-quality image generation in pixel space which contains data consistency and discrepancy mitigation in a one-step reconstruction process. The cascaded framework minimizes computational costs by moving some inference steps from pixel space to latent space. The discrepancy mitigation technique addresses the training-sampling gap induced by data consistency, ensuring the data distribution is close to the original manifold. A specialized Alternating Direction Method of Multipliers (ADMM) is employed to process image gradients in separate directions, offering a more targeted approach to regularization. Experimental results across two datasets demonstrate CDDM's superior performance in high-quality image generation with clearer boundaries compared to existing methods, highlighting the framework's computational efficiency.
A theory of volumetric representations for opaque solids
Dec 24, 2023We develop a theory for the representation of opaque solids as volumetric models. Starting from a stochastic representation of opaque solids as random indicator functions, we prove the conditions under which such solids can be modeled using exponential volumetric transport. We also derive expressions for the volumetric attenuation coefficient as a functional of the probability distributions of the underlying indicator functions. We generalize our theory to account for isotropic and anisotropic scattering at different parts of the solid, and for representations of opaque solids as implicit surfaces. We derive our volumetric representation from first principles, which ensures that it satisfies physical constraints such as reciprocity and reversibility. We use our theory to explain, compare, and correct previous volumetric representations, as well as propose meaningful extensions that lead to improved performance in 3D reconstruction tasks.
Redistribution Mechanism Design on Networks
Oct 21, 2019
Redistribution mechanisms have been proposed for more efficient resource allocation but not for profit. We consider redistribution mechanism design for the first time in a setting where participants are connected and the resource owner is only aware of her neighbours. In this setting, to make the resource allocation more efficient, the resource owner has to inform the others who are not her neighbours, but her neighbours do not want more participants to compete with them. Hence, the goal is to design a redistribution mechanism such that participants are incentivized to invite more participants and the resource owner does not earn or lose much money from the allocation. We first show that existing redistribution mechanisms cannot be directly applied in the network setting to achieve the goal. Then we propose a novel network-based redistribution mechanism such that all participants in the network are invited, the allocation is more efficient and the resource owner has no deficit.