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Lars E. Peterson

Predicting Opioid Use Disorder from Longitudinal Healthcare Data using Multi-stream Transformer

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Mar 16, 2021
Sajjad Fouladvand, Jeffery Talbert, Linda P. Dwoskin, Heather Bush, Amy Lynn Meadows, Lars E. Peterson, Ramakanth Kavuluru, Jin Chen

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Opioid Use Disorder (OUD) is a public health crisis costing the US billions of dollars annually in healthcare, lost workplace productivity, and crime. Analyzing longitudinal healthcare data is critical in addressing many real-world problems in healthcare. Leveraging the real-world longitudinal healthcare data, we propose a novel multi-stream transformer model called MUPOD for OUD prediction. MUPOD is designed to simultaneously analyze multiple types of healthcare data streams, such as medications and diagnoses, by finding the attentions within and across these data streams. Our model tested on the data from 392,492 patients with long-term back pain problems showed significantly better performance than the traditional models and recently developed deep learning models.

* This paper is under consideration for the AMIA 2021 Annual Symposim 
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