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Pete Lowery

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Learning Generic Lung Ultrasound Biomarkers for Decoupling Feature Extraction from Downstream Tasks

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Jun 16, 2022
Gautam Rajendrakumar Gare, Tom Fox, Pete Lowery, Kevin Zamora, Hai V. Tran, Laura Hutchins, David Montgomery, Amita Krishnan, Deva Kannan Ramanan, Ricardo Luis Rodriguez, Bennett P deBoisblanc, John Michael Galeotti

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Contemporary artificial neural networks (ANN) are trained end-to-end, jointly learning both features and classifiers for the task of interest. Though enormously effective, this paradigm imposes significant costs in assembling annotated task-specific datasets and training large-scale networks. We propose to decouple feature learning from downstream lung ultrasound tasks by introducing an auxiliary pre-task of visual biomarker classification. We demonstrate that one can learn an informative, concise, and interpretable feature space from ultrasound videos by training models for predicting biomarker labels. Notably, biomarker feature extractors can be trained from data annotated with weak video-scale supervision. These features can be used by a variety of downstream Expert models targeted for diverse clinical tasks (Diagnosis, lung severity, S/F ratio). Crucially, task-specific expert models are comparable in accuracy to end-to-end models directly trained for such target tasks, while being significantly lower cost to train.

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The Role of Pleura and Adipose in Lung Ultrasound AI

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Jan 19, 2022
Gautam Rajendrakumar Gare, Wanwen Chen, Alex Ling Yu Hung, Edward Chen, Hai V. Tran, Tom Fox, Pete Lowery, Kevin Zamora, Bennett P deBoisblanc, Ricardo Luis Rodriguez, John Michael Galeotti

In this paper, we study the significance of the pleura and adipose tissue in lung ultrasound AI analysis. We highlight their more prominent appearance when using high-frequency linear (HFL) instead of curvilinear ultrasound probes, showing HFL reveals better pleura detail. We compare the diagnostic utility of the pleura and adipose tissue using an HFL ultrasound probe. Masking the adipose tissue during training and inference (while retaining the pleural line and Merlin's space artifacts such as A-lines and B-lines) improved the AI model's diagnostic accuracy.

* LL-COVID19 2021. Lecture Notes in Computer Science, vol 12969. Springer, Cham  
* Published in MICCAI 2021 workshop on Lessons Learned from the development and application of medical imaging-based AI technologies for combating COVID-19 (LL-COVID19). The first two authors contributed equally to this work 
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