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UWAFA-GAN: Ultra-Wide-Angle Fluorescein Angiography Transformation via Multi-scale Generation and Registration Enhancement
May 01, 2024
Fundus photography, in combination with the ultra-wide-angle fundus (UWF) techniques, becomes an indispensable diagnostic tool in clinical settings by offering a more comprehensive view of the retina. Nonetheless, UWF fluorescein angiography (UWF-FA) necessitates the administration of a fluorescent dye via injection into the patient's hand or elbow unlike UWF scanning laser ophthalmoscopy (UWF-SLO). To mitigate potential adverse effects associated with injections, researchers have proposed the development of cross-modality medical image generation algorithms capable of converting UWF-SLO images into their UWF-FA counterparts. Current image generation techniques applied to fundus photography encounter difficulties in producing high-resolution retinal images, particularly in capturing minute vascular lesions. To address these issues, we introduce a novel conditional generative adversarial network (UWAFA-GAN) to synthesize UWF-FA from UWF-SLO. This approach employs multi-scale generators and an attention transmit module to efficiently extract both global structures and local lesions. Additionally, to counteract the image blurriness issue that arises from training with misaligned data, a registration module is integrated within this framework. Our method performs non-trivially on inception scores and details generation. Clinical user studies further indicate that the UWF-FA images generated by UWAFA-GAN are clinically comparable to authentic images in terms of diagnostic reliability. Empirical evaluations on our proprietary UWF image datasets elucidate that UWAFA-GAN outperforms extant methodologies. The code is accessible at https://github.com/Tinysqua/UWAFA-GAN.
ConsistencyDet: A Robust Object Detector with a Denoising Paradigm of Consistency Model
Apr 17, 2024Object detection, a quintessential task in the realm of perceptual computing, can be tackled using a generative methodology. In the present study, we introduce a novel framework designed to articulate object detection as a denoising diffusion process, which operates on the perturbed bounding boxes of annotated entities. This framework, termed ConsistencyDet, leverages an innovative denoising concept known as the Consistency Model. The hallmark of this model is its self-consistency feature, which empowers the model to map distorted information from any temporal stage back to its pristine state, thereby realizing a "one-step denoising" mechanism. Such an attribute markedly elevates the operational efficiency of the model, setting it apart from the conventional Diffusion Model. Throughout the training phase, ConsistencyDet initiates the diffusion sequence with noise-infused boxes derived from the ground-truth annotations and conditions the model to perform the denoising task. Subsequently, in the inference stage, the model employs a denoising sampling strategy that commences with bounding boxes randomly sampled from a normal distribution. Through iterative refinement, the model transforms an assortment of arbitrarily generated boxes into definitive detections. Comprehensive evaluations employing standard benchmarks, such as MS-COCO and LVIS, corroborate that ConsistencyDet surpasses other leading-edge detectors in performance metrics. Our code is available at https://github.com/Tankowa/ConsistencyDet.
ConsistencyDet: Robust Object Detector with Denoising Paradigm of Consistency Model
Apr 11, 2024Object detection, a quintessential task in the realm of perceptual computing, can be tackled using a generative methodology. In the present study, we introduce a novel framework designed to articulate object detection as a denoising diffusion process, which operates on perturbed bounding boxes of annotated entities. This framework, termed ConsistencyDet, leverages an innovative denoising concept known as the Consistency Model. The hallmark of this model is its self-consistency feature, which empowers the model to map distorted information from any temporal stage back to its pristine state, thereby realizing a ``one-step denoising'' mechanism. Such an attribute markedly elevates the operational efficiency of the model, setting it apart from the conventional Diffusion Model. Throughout the training phase, ConsistencyDet initiates the diffusion sequence with noise-infused boxes derived from the ground-truth annotations and conditions the model to perform the denoising task. Subsequently, in the inference stage, the model employs a denoising sampling strategy that commences with bounding boxes randomly sampled from a normal distribution. Through iterative refinement, the model transforms an assortment of arbitrarily generated boxes into the definitive detections. Comprehensive evaluations employing standard benchmarks, such as MS-COCO and LVIS, corroborate that ConsistencyDet surpasses other leading-edge detectors in performance metrics.
VQ-NeRV: A Vector Quantized Neural Representation for Videos
Mar 19, 2024
Implicit neural representations (INR) excel in encoding videos within neural networks, showcasing promise in computer vision tasks like video compression and denoising. INR-based approaches reconstruct video frames from content-agnostic embeddings, which hampers their efficacy in video frame regression and restricts their generalization ability for video interpolation. To address these deficiencies, Hybrid Neural Representation for Videos (HNeRV) was introduced with content-adaptive embeddings. Nevertheless, HNeRV's compression ratios remain relatively low, attributable to an oversight in leveraging the network's shallow features and inter-frame residual information. In this work, we introduce an advanced U-shaped architecture, Vector Quantized-NeRV (VQ-NeRV), which integrates a novel component--the VQ-NeRV Block. This block incorporates a codebook mechanism to discretize the network's shallow residual features and inter-frame residual information effectively. This approach proves particularly advantageous in video compression, as it results in smaller size compared to quantized features. Furthermore, we introduce an original codebook optimization technique, termed shallow codebook optimization, designed to refine the utility and efficiency of the codebook. The experimental evaluations indicate that VQ-NeRV outperforms HNeRV on video regression tasks, delivering superior reconstruction quality (with an increase of 1-2 dB in Peak Signal-to-Noise Ratio (PSNR)), better bit per pixel (bpp) efficiency, and improved video inpainting outcomes.
stMCDI: Masked Conditional Diffusion Model with Graph Neural Network for Spatial Transcriptomics Data Imputation
Mar 16, 2024
Spatially resolved transcriptomics represents a significant advancement in single-cell analysis by offering both gene expression data and their corresponding physical locations. However, this high degree of spatial resolution entails a drawback, as the resulting spatial transcriptomic data at the cellular level is notably plagued by a high incidence of missing values. Furthermore, most existing imputation methods either overlook the spatial information between spots or compromise the overall gene expression data distribution. To address these challenges, our primary focus is on effectively utilizing the spatial location information within spatial transcriptomic data to impute missing values, while preserving the overall data distribution. We introduce \textbf{stMCDI}, a novel conditional diffusion model for spatial transcriptomics data imputation, which employs a denoising network trained using randomly masked data portions as guidance, with the unmasked data serving as conditions. Additionally, it utilizes a GNN encoder to integrate the spatial position information, thereby enhancing model performance. The results obtained from spatial transcriptomics datasets elucidate the performance of our methods relative to existing approaches.
PE-MVCNet: Multi-view and Cross-modal Fusion Network for Pulmonary Embolism Prediction
Feb 29, 2024The early detection of a pulmonary embolism (PE) is critical for enhancing patient survival rates. Both image-based and non-image-based features are of utmost importance in medical classification tasks. In a clinical setting, physicians tend to rely on the contextual information provided by Electronic Medical Records (EMR) to interpret medical imaging. However, very few models effectively integrate clinical information with imaging data. To address this shortcoming, we suggest a multimodal fusion methodology, termed PE-MVCNet, which capitalizes on Computed Tomography Pulmonary Angiography imaging and EMR data. This method comprises the Image-only module with an integrated multi-view block, the EMR-only module, and the Cross-modal Attention Fusion (CMAF) module. These modules cooperate to extract comprehensive features that subsequently generate predictions for PE. We conducted experiments using the publicly accessible Stanford University Medical Center dataset, achieving an AUROC of 94.1%, an accuracy rate of 90.2%, and an F1 score of 90.6%. Our proposed model outperforms existing methodologies, corroborating that our multimodal fusion model excels compared to models that use a single data modality. Our source code is available at https://github.com/LeavingStarW/PE-MVCNET.
Semi-supervised Medical Image Segmentation Method Based on Cross-pseudo Labeling Leveraging Strong and Weak Data Augmentation Strategies
Feb 17, 2024Traditional supervised learning methods have historically encountered certain constraints in medical image segmentation due to the challenging collection process, high labeling cost, low signal-to-noise ratio, and complex features characterizing biomedical images. This paper proposes a semi-supervised model, DFCPS, which innovatively incorporates the Fixmatch concept. This significantly enhances the model's performance and generalizability through data augmentation processing, employing varied strategies for unlabeled data. Concurrently, the model design gives appropriate emphasis to the generation, filtration, and refinement processes of pseudo-labels. The novel concept of cross-pseudo-supervision is introduced, integrating consistency learning with self-training. This enables the model to fully leverage pseudo-labels from multiple perspectives, thereby enhancing training diversity. The DFCPS model is compared with both baseline and advanced models using the publicly accessible Kvasir-SEG dataset. Across all four subdivisions containing different proportions of unlabeled data, our model consistently exhibits superior performance. Our source code is available at https://github.com/JustlfC03/DFCPS.
* 5 pages, 2 figures, accept ISBI2024
ICHPro: Intracerebral Hemorrhage Prognosis Classification Via Joint-attention Fusion-based 3d Cross-modal Network
Feb 17, 2024Intracerebral Hemorrhage (ICH) is the deadliest subtype of stroke, necessitating timely and accurate prognostic evaluation to reduce mortality and disability. However, the multi-factorial nature and complexity of ICH make methods based solely on computed tomography (CT) image features inadequate. Despite the capacity of cross-modal networks to fuse additional information, the effective combination of different modal features remains a significant challenge. In this study, we propose a joint-attention fusion-based 3D cross-modal network termed ICHPro that simulates the ICH prognosis interpretation process utilized by neurosurgeons. ICHPro includes a joint-attention fusion module to fuse features from CT images with demographic and clinical textual data. To enhance the representation of cross-modal features, we introduce a joint loss function. ICHPro facilitates the extraction of richer cross-modal features, thereby improving classification performance. Upon testing our method using a five-fold cross-validation, we achieved an accuracy of 89.11%, an F1 score of 0.8767, and an AUC value of 0.9429. These results outperform those obtained from other advanced methods based on the test dataset, thereby demonstrating the superior efficacy of ICHPro. The code is available at our Github: https://github.com/YU-deep/ICH.
TC-DiffRecon: Texture coordination MRI reconstruction method based on diffusion model and modified MF-UNet method
Feb 17, 2024Recently, diffusion models have gained significant attention as a novel set of deep learning-based generative methods. These models attempt to sample data from a Gaussian distribution that adheres to a target distribution, and have been successfully adapted to the reconstruction of MRI data. However, as an unconditional generative model, the diffusion model typically disrupts image coordination because of the consistent projection of data introduced by conditional bootstrap. This often results in image fragmentation and incoherence. Furthermore, the inherent limitations of the diffusion model often lead to excessive smoothing of the generated images. In the same vein, some deep learning-based models often suffer from poor generalization performance, meaning their effectiveness is greatly affected by different acceleration factors. To address these challenges, we propose a novel diffusion model-based MRI reconstruction method, named TC-DiffRecon, which does not rely on a specific acceleration factor for training. We also suggest the incorporation of the MF-UNet module, designed to enhance the quality of MRI images generated by the model while mitigating the over-smoothing issue to a certain extent. During the image generation sampling process, we employ a novel TCKG module and a Coarse-to-Fine sampling scheme. These additions aim to harmonize image texture, expedite the sampling process, while achieving data consistency. Our source code is available at https://github.com/JustlfC03/TC-DiffRecon.
* 5 pages, 2 figures, accept ISBI2024
LKFormer: Large Kernel Transformer for Infrared Image Super-Resolution
Jan 24, 2024Given the broad application of infrared technology across diverse fields, there is an increasing emphasis on investigating super-resolution techniques for infrared images within the realm of deep learning. Despite the impressive results of current Transformer-based methods in image super-resolution tasks, their reliance on the self-attentive mechanism intrinsic to the Transformer architecture results in images being treated as one-dimensional sequences, thereby neglecting their inherent two-dimensional structure. Moreover, infrared images exhibit a uniform pixel distribution and a limited gradient range, posing challenges for the model to capture effective feature information. Consequently, we suggest a potent Transformer model, termed Large Kernel Transformer (LKFormer), to address this issue. Specifically, we have designed a Large Kernel Residual Attention (LKRA) module with linear complexity. This mainly employs depth-wise convolution with large kernels to execute non-local feature modeling, thereby substituting the standard self-attentive layer. Additionally, we have devised a novel feed-forward network structure called Gated-Pixel Feed-Forward Network (GPFN) to augment the LKFormer's capacity to manage the information flow within the network. Comprehensive experimental results reveal that our method surpasses the most advanced techniques available, using fewer parameters and yielding considerably superior performance.The source code will be available at https://github.com/sad192/large-kernel-Transformer.