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Relationship Discovery for Drug Recommendation
Apr 18, 2024
Medication recommendation systems are designed to deliver personalized drug suggestions that are closely aligned with individual patient needs. Previous studies have primarily concentrated on developing medication embeddings, achieving significant progress. Nonetheless, these approaches often fall short in accurately reflecting individual patient profiles, mainly due to challenges in distinguishing between various patient conditions and the inability to establish precise correlations between specific conditions and appropriate medications. In response to these issues, we introduce DisMed, a model that focuses on patient conditions to enhance personalization. DisMed employs causal inference to discern clear, quantifiable causal links. It then examines patient conditions in depth, recognizing and adapting to the evolving nuances of these conditions, and mapping them directly to corresponding medications. Additionally, DisMed leverages data from multiple patient visits to propose combinations of medications. Comprehensive testing on real-world datasets demonstrates that DisMed not only improves the customization of patient profiles but also surpasses leading models in both precision and safety.
Knowledge-Aware Multi-Intent Contrastive Learning for Multi-Behavior Recommendation
Apr 18, 2024Multi-behavioral recommendation optimizes user experiences by providing users with more accurate choices based on their diverse behaviors, such as view, add to cart, and purchase. Current studies on multi-behavioral recommendation mainly explore the connections and differences between multi-behaviors from an implicit perspective. Specifically, they directly model those relations using black-box neural networks. In fact, users' interactions with items under different behaviors are driven by distinct intents. For instance, when users view products, they tend to pay greater attention to information such as ratings and brands. However, when it comes to the purchasing phase, users become more price-conscious. To tackle this challenge and data sparsity problem in the multi-behavioral recommendation, we propose a novel model: Knowledge-Aware Multi-Intent Contrastive Learning (KAMCL) model. This model uses relationships in the knowledge graph to construct intents, aiming to mine the connections between users' multi-behaviors from the perspective of intents to achieve more accurate recommendations. KAMCL is equipped with two contrastive learning schemes to alleviate the data scarcity problem and further enhance user representations. Extensive experiments on three real datasets demonstrate the superiority of our model.
Closely Interactive Human Reconstruction with Proxemics and Physics-Guided Adaption
Apr 17, 2024Existing multi-person human reconstruction approaches mainly focus on recovering accurate poses or avoiding penetration, but overlook the modeling of close interactions. In this work, we tackle the task of reconstructing closely interactive humans from a monocular video. The main challenge of this task comes from insufficient visual information caused by depth ambiguity and severe inter-person occlusion. In view of this, we propose to leverage knowledge from proxemic behavior and physics to compensate the lack of visual information. This is based on the observation that human interaction has specific patterns following the social proxemics. Specifically, we first design a latent representation based on Vector Quantised-Variational AutoEncoder (VQ-VAE) to model human interaction. A proxemics and physics guided diffusion model is then introduced to denoise the initial distribution. We design the diffusion model as dual branch with each branch representing one individual such that the interaction can be modeled via cross attention. With the learned priors of VQ-VAE and physical constraint as the additional information, our proposed approach is capable of estimating accurate poses that are also proxemics and physics plausible. Experimental results on Hi4D, 3DPW, and CHI3D demonstrate that our method outperforms existing approaches. The code is available at \url{https://github.com/boycehbz/HumanInteraction}.
Portrait3D: Text-Guided High-Quality 3D Portrait Generation Using Pyramid Representation and GANs Prior
Apr 16, 2024Existing neural rendering-based text-to-3D-portrait generation methods typically make use of human geometry prior and diffusion models to obtain guidance. However, relying solely on geometry information introduces issues such as the Janus problem, over-saturation, and over-smoothing. We present Portrait3D, a novel neural rendering-based framework with a novel joint geometry-appearance prior to achieve text-to-3D-portrait generation that overcomes the aforementioned issues. To accomplish this, we train a 3D portrait generator, 3DPortraitGAN-Pyramid, as a robust prior. This generator is capable of producing 360{\deg} canonical 3D portraits, serving as a starting point for the subsequent diffusion-based generation process. To mitigate the "grid-like" artifact caused by the high-frequency information in the feature-map-based 3D representation commonly used by most 3D-aware GANs, we integrate a novel pyramid tri-grid 3D representation into 3DPortraitGAN-Pyramid. To generate 3D portraits from text, we first project a randomly generated image aligned with the given prompt into the pre-trained 3DPortraitGAN-Pyramid's latent space. The resulting latent code is then used to synthesize a pyramid tri-grid. Beginning with the obtained pyramid tri-grid, we use score distillation sampling to distill the diffusion model's knowledge into the pyramid tri-grid. Following that, we utilize the diffusion model to refine the rendered images of the 3D portrait and then use these refined images as training data to further optimize the pyramid tri-grid, effectively eliminating issues with unrealistic color and unnatural artifacts. Our experimental results show that Portrait3D can produce realistic, high-quality, and canonical 3D portraits that align with the prompt.
Enhancing the Performance of Aspect-Based Sentiment Analysis Systems
Apr 04, 2024Aspect-based sentiment analysis aims to predict sentiment polarity with fine granularity. While Graph Convolutional Networks (GCNs) are widely utilized for sentimental feature extraction, their naive application for syntactic feature extraction can compromise information preservation. This study introduces an innovative edge-enhanced GCN, named SentiSys, to navigate the syntactic graph while preserving intact feature information, leading to enhanced performance. Specifically,we first integrate a bidirectional long short-term memory (Bi-LSTM) network and a self-attention-based transformer. This combination facilitates effective text encoding, preventing the loss of information and predicting long dependency text. A bidirectional GCN (Bi-GCN) with message passing is then employed to encode relationships between entities. Additionally, unnecessary information is filtered out using an aspect-specific masking technique. To validate the effectiveness of our proposed model, we conduct extensive evaluation experiments and ablation studies on four benchmark datasets. The results consistently demonstrate improved performance in aspect-based sentiment analysis when employing SentiSys. This approach successfully addresses the challenges associated with syntactic feature extraction, highlighting its potential for advancing sentiment analysis methodologies.
DiSR-NeRF: Diffusion-Guided View-Consistent Super-Resolution NeRF
Apr 01, 2024We present DiSR-NeRF, a diffusion-guided framework for view-consistent super-resolution (SR) NeRF. Unlike prior works, we circumvent the requirement for high-resolution (HR) reference images by leveraging existing powerful 2D super-resolution models. Nonetheless, independent SR 2D images are often inconsistent across different views. We thus propose Iterative 3D Synchronization (I3DS) to mitigate the inconsistency problem via the inherent multi-view consistency property of NeRF. Specifically, our I3DS alternates between upscaling low-resolution (LR) rendered images with diffusion models, and updating the underlying 3D representation with standard NeRF training. We further introduce Renoised Score Distillation (RSD), a novel score-distillation objective for 2D image resolution. Our RSD combines features from ancestral sampling and Score Distillation Sampling (SDS) to generate sharp images that are also LR-consistent. Qualitative and quantitative results on both synthetic and real-world datasets demonstrate that our DiSR-NeRF can achieve better results on NeRF super-resolution compared with existing works. Code and video results available at the project website.
ST-LLM: Large Language Models Are Effective Temporal Learners
Mar 30, 2024Large Language Models (LLMs) have showcased impressive capabilities in text comprehension and generation, prompting research efforts towards video LLMs to facilitate human-AI interaction at the video level. However, how to effectively encode and understand videos in video-based dialogue systems remains to be solved. In this paper, we investigate a straightforward yet unexplored question: Can we feed all spatial-temporal tokens into the LLM, thus delegating the task of video sequence modeling to the LLMs? Surprisingly, this simple approach yields significant improvements in video understanding. Based upon this, we propose ST-LLM, an effective video-LLM baseline with Spatial-Temporal sequence modeling inside LLM. Furthermore, to address the overhead and stability issues introduced by uncompressed video tokens within LLMs, we develop a dynamic masking strategy with tailor-made training objectives. For particularly long videos, we have also designed a global-local input module to balance efficiency and effectiveness. Consequently, we harness LLM for proficient spatial-temporal modeling, while upholding efficiency and stability. Extensive experimental results attest to the effectiveness of our method. Through a more concise model and training pipeline, ST-LLM establishes a new state-of-the-art result on VideoChatGPT-Bench and MVBench. Codes have been available at https://github.com/TencentARC/ST-LLM.
Molecular Generative Adversarial Network with Multi-Property Optimization
Mar 29, 2024Deep generative models, such as generative adversarial networks (GANs), have been employed for $de~novo$ molecular generation in drug discovery. Most prior studies have utilized reinforcement learning (RL) algorithms, particularly Monte Carlo tree search (MCTS), to handle the discrete nature of molecular representations in GANs. However, due to the inherent instability in training GANs and RL models, along with the high computational cost associated with MCTS sampling, MCTS RL-based GANs struggle to scale to large chemical databases. To tackle these challenges, this study introduces a novel GAN based on actor-critic RL with instant and global rewards, called InstGAN, to generate molecules at the token-level with multi-property optimization. Furthermore, maximized information entropy is leveraged to alleviate the mode collapse. The experimental results demonstrate that InstGAN outperforms other baselines, achieves comparable performance to state-of-the-art models, and efficiently generates molecules with multi-property optimization. The source code will be released upon acceptance of the paper.
Enhancing Industrial Transfer Learning with Style Filter: Cost Reduction and Defect-Focus
Mar 25, 2024Addressing the challenge of data scarcity in industrial domains, transfer learning emerges as a pivotal paradigm. This work introduces Style Filter, a tailored methodology for industrial contexts. By selectively filtering source domain data before knowledge transfer, Style Filter reduces the quantity of data while maintaining or even enhancing the performance of transfer learning strategy. Offering label-free operation, minimal reliance on prior knowledge, independence from specific models, and re-utilization, Style Filter is evaluated on authentic industrial datasets, highlighting its effectiveness when employed before conventional transfer strategies in the deep learning domain. The results underscore the effectiveness of Style Filter in real-world industrial applications.
Tackling the Singularities at the Endpoints of Time Intervals in Diffusion Models
Mar 20, 2024
Most diffusion models assume that the reverse process adheres to a Gaussian distribution. However, this approximation has not been rigorously validated, especially at singularities, where t=0 and t=1. Improperly dealing with such singularities leads to an average brightness issue in applications, and limits the generation of images with extreme brightness or darkness. We primarily focus on tackling singularities from both theoretical and practical perspectives. Initially, we establish the error bounds for the reverse process approximation, and showcase its Gaussian characteristics at singularity time steps. Based on this theoretical insight, we confirm the singularity at t=1 is conditionally removable while it at t=0 is an inherent property. Upon these significant conclusions, we propose a novel plug-and-play method SingDiffusion to address the initial singular time step sampling, which not only effectively resolves the average brightness issue for a wide range of diffusion models without extra training efforts, but also enhances their generation capability in achieving notable lower FID scores.